Mac Pro Memory for 2010 Model 5,1 (6-Core and 12-Core)
Mac Pro Mid 2010
8 slot and 4 slot versions
DDR3-1333Mhz
The DDR3-1333 DIMMs for the 2010 Mac Pro require a Thermal Sensor for full performance and compatibility. Many 3rd party Mac Pro DIMMs do not include this sensor. Ramjet memory always conforms 100% to the Apple specification. These DIMMs include the Apple thermal sensor.
Tri-channel memory configuration gives a slight performance advantage. The DDR3-1333 DIMMs for the Mac Pro will run 1-3% faster if they are installed in matched sets of three (tri-channel). You may add DIMMs in any combination, but performance will suffer slightly if the DIMMs are not matched 3x at a time.
Non-Mixable 16GB DIMMs: 16GB DIMMs can ONLY be used with identical 16GB DIMMs from the same batch (i.e. ordered at the same time.) Utilization of 16GBx8 memory modules requires OS X Mavericks (10.9.X.) Previous operating systems are limited to a maximum of 96GB (16GBx6.)
Matched Modules: The Ramjet kits for the Mac Pro DDR3-1333 contain a matched set of DIMMs. The kit will consist of identical brand/model/spec IC's. They will be from a single batch, and will have matching series numbers. This ensures maximum performance, and perfect compatibility.
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The following installation video covers the Mac Pro DDR3-1333.
Apple's user manual can provide you more details about 2010 Mac Pro Model 5,1. Click here for Apple's installation guide (PDF.)